Sigma Compounds (sigmacompounds.com) is a premium research peptide company headquartered in Overland Park, Kansas, operating at the forefront of the research peptide industry. Founded by Matthew -- a well-known and publicly recognized advocate for peptide education and research -- Sigma Compounds is one of the few companies in the space with genuine accountability and a reputation behind the brand name. Customers consistently cite the combination of Matthew's visible involvement, the company's educational content library, and the product quality as what sets Sigma apart from the dozens of anonymous peptide vendors in the market.

Sigma Compounds sources all products through partnerships with manufacturers who meet ISO 9001:2008 quality management standards -- the internationally recognized certification for quality management systems. Every batch is third-party tested for purity, potency, identity, heavy metals, and microbial contamination before being made available to customers. Products arrive in boutique-style packaging with individual care taken to ensure sterile conditions are maintained throughout shipping, including proper cold-chain management for temperature-sensitive compounds.

The company operates on a 100% satisfaction guarantee and provides free shipping on all orders over $100. Customer service is consistently praised for responsiveness -- including direct contact with the owner/founder on complex inquiries, a level of personal engagement virtually unheard of in the research peptide space.

All Sigma Compounds products are furnished for laboratory research use only and must be handled by qualified, licensed professionals in accordance with all applicable regulations.

What Sigma Compounds Offers

Individual Research Peptides (Vials):

Tissue Repair and Recovery:

• BPC-157 5mg (https://sigmacompounds.com/products/bpc-157/) -- Body Protection Compound-157, a synthetic pentadecapeptide derived from a protective protein in human gastric juice. Among the most extensively researched healing peptides in the field, with documented effects on tendon-to-bone healing, muscle repair, angiogenesis, gut protection, neurological protection, and systemic anti-inflammatory signaling. Often called the "wolverine peptide" for its multi-system protective scope. 10% off with code greats10
• BPC-157 10mg (https://sigmacompounds.com/products/bpc-157-10-mg/) -- High-dose vial of BPC-157 for extended research protocols or bulk research use. Same purity and manufacturing standards as the 5mg format. 10% off with code greats10
• TB-500 10mg (https://sigmacompounds.com/products/tb-500/) -- Thymosin Beta-4 (TB-500 fragment 17-23), a synthetic peptide corresponding to the bioactive fragment of the endogenous protein thymosin beta-4. TB-500 works through actin polymerization, cell migration stimulation, and VEGF-mediated angiogenesis -- mechanistically distinct from BPC-157 and widely studied in combination with it for synergistic repair effects. 10% off with code greats10

Anti-Aging and Longevity:

• NAD+ 500mg (https://sigmacompounds.com/products/nad-500mg/) -- Nicotinamide adenine dinucleotide, the foundational coenzyme in cellular energy metabolism and DNA repair. NAD+ levels decline significantly with age. The 500mg format for research protocols studying NAD+'s role in mitochondrial function, sirtuin activation, and metabolic regulation. 10% off with code greats10
• NAD+ 1000mg (https://sigmacompounds.com/products/nad-1000mg/) -- High-dose NAD+ for extended research protocols. 10% off with code greats10
• GHK-Cu 50mg (https://sigmacompounds.com/products/ghk-cu/) -- Copper peptide GHK-Cu (glycyl-L-histidyl-L-lysine:copper), one of the most researched anti-aging peptides, with documented effects on collagen synthesis, wound healing, anti-inflammatory activity, and tissue regeneration. Naturally occurring in human plasma, the GHK-Cu tripeptide declines with age. Studied extensively for skin regeneration and as a component of anti-aging research protocols. 10% off with code greats10
• GHK-Cu 100mg (https://sigmacompounds.com/products/ghk-cu-100mg/) -- High-dose copper peptide for extended skin regeneration and anti-aging research. 10% off with code greats10
• Epithalon 10mg (https://sigmacompounds.com/products/epithalon/) -- A tetrapeptide (Ala-Glu-Asp-Gly) derived from the pineal gland, studied for its effects on telomerase activation and telomere length extension -- among the most discussed longevity mechanisms in anti-aging research. 10% off with code greats10
• SS-31 10mg (https://sigmacompounds.com/products/ss-31-10mg/) -- Elamipretide (SS-31), a mitochondria-targeted antioxidant peptide that selectively accumulates in the inner mitochondrial membrane. Studied for its ability to reduce oxidative stress at the mitochondrial level and support mitochondrial bioenergetics in aging research. 10% off with code greats10
• MOTS-C 10mg (https://sigmacompounds.com/products/mots-c/) -- A mitochondrial-derived peptide (encoded in the mitochondrial genome) with documented metabolic regulatory functions including glucose metabolism support and exercise-mimetic effects. Among the newest and most interesting compounds in the longevity research space. 10% off with code greats10

Growth Hormone and Metabolic:

• Sermorelin 5mg (https://sigmacompounds.com/products/sermorelin/) -- A 29-amino acid analogue of GHRH (growth hormone-releasing hormone), studied for its ability to stimulate pituitary GH secretion through endogenous pathways. Often researched for body composition, sleep quality, and recovery applications. 10% off with code greats10
• Sermorelin 10mg (https://sigmacompounds.com/products/sermorelin-10mg/) -- High-dose Sermorelin for extended research. 10% off with code greats10
• Ipamorelin 5mg (https://sigmacompounds.com/products/ipamorelin/) -- A selective GH secretagogue and ghrelin receptor agonist, frequently researched in combination with CJC-1295 for synergistic GH release. One of the most studied peptides in the growth hormone secretagogue category. 10% off with code greats10
• Ipamorelin 10mg (https://sigmacompounds.com/products/ipamorelin-10mg/) -- High-dose Ipamorelin. 10% off with code greats10
• CJC-1295 DAC 5mg (https://sigmacompounds.com/products/cjc-1295-dac/) -- A long-acting GHRH analogue with Drug Affinity Complex (DAC) technology that extends its half-life to approximately 6-8 days, compared to minutes for native GHRH. Widely studied for sustained GH pulse research. 10% off with code greats10
• CJC-1295 DAC 10mg (https://sigmacompounds.com/products/cjc-1295-dac-10mg/) -- High-dose long-acting GHRH analogue. 10% off with code greats10
• Tesamorelin 10mg (https://sigmacompounds.com/products/tesamorelin/) -- A stabilized analogue of GHRH (growth hormone-releasing hormone), studied primarily for visceral adipose tissue research and body composition applications. 10% off with code greats10
• IGF-1 LR3 1mg (https://sigmacompounds.com/products/igf-1-lr3/) -- A long-acting analogue of Insulin-Like Growth Factor-1 with an arginine-3 substitution that reduces IGF binding protein affinity and extends the half-life from minutes to approximately 20-30 hours. Studied for muscle protein synthesis and tissue repair research. 10% off with code greats10
• GLP-1 C 10mg (https://sigmacompounds.com/products/glp-1-c/) -- A GLP-1 receptor agonist analogue studied for metabolic research including glucose metabolism and satiety signaling. 10% off with code greats10
• GLP-3 R 10mg (https://sigmacompounds.com/products/glp-3-r/) -- GLP-3 receptor agonist research compound for metabolic pathway research. 10% off with code greats10
• AOD-9604 10mg -- A fragment of human growth hormone (HGH) containing amino acids 176-191. Studied for its fat metabolism effects without the growth-promoting properties of full HGH. 10% off with code greats10

Cognitive and Neurological (Nootropics):

• Selank 10mg (https://sigmacompounds.com/products/selank-10-mg-2/) -- A synthetic heptapeptide analogue of the human immunoglobulin tetrapeptide tuftsin, developed and studied in Russia as an anxiolytic and nootropic compound. Selank is uniquely notable for its anxiolytic properties without the sedation, dependence, or cognitive impairment associated with benzodiazepines. Studied for anxiety reduction, cognitive enhancement, memory improvement, and mood stabilization. Available as both injectable vial and nasal spray. 10% off with code greats10
• Semax 10mg (https://sigmacompounds.com/products/semax/) -- A synthetic heptapeptide analogue of ACTH developed in Russia, studied extensively for cognitive enhancement through BDNF (brain-derived neurotrophic factor) upregulation, neuroprotection, and attention/focus improvement. One of the most researched nootropic peptides available. Available as both injectable vial and nasal spray. 10% off with code greats10
• DSIP 5mg (https://sigmacompounds.com/products/dsip/) -- Delta Sleep-Inducing Peptide, a naturally occurring nonapeptide studied for its role in sleep regulation, stress response, and circadian rhythm support. 10% off with code greats10

Immune and Inflammatory:

• Thymosin Alpha-1 10mg (https://sigmacompounds.com/products/thymosin-alpha-1/) -- A 28-amino acid peptide naturally produced by the thymus, studied extensively as an immune modulator. Thymosin Alpha-1 has been studied for immune function restoration in immunocompromised states, antiviral and antitumor applications, and sepsis management. One of the most clinically developed peptides available for research. 10% off with code greats10
• KPV 10mg (https://sigmacompounds.com/products/kpv/) -- A tripeptide (Lys-Pro-Val) derived from alpha-MSH with documented anti-inflammatory effects through NF-kB pathway modulation and IL-8 reduction. Studied for gut inflammation, skin conditions, and systemic anti-inflammatory research. 10% off with code greats10
• LL-37 5mg (https://sigmacompounds.com/products/ll-37/) -- A cathelicidin-derived antimicrobial peptide and the only known member of the cathelicidin family expressed in humans. Studied for broad-spectrum antimicrobial activity, wound healing, immune modulation, and anti-biofilm properties. 10% off with code greats10
• VIP 10mg (https://sigmacompounds.com/products/vip/) -- Vasoactive Intestinal Peptide, a 28-amino acid neuropeptide with documented anti-inflammatory, vasodilatory, and immunomodulatory properties. Studied for autoimmune conditions, pulmonary arterial hypertension, and neuroprotection. 10% off with code greats10
• ARA-290 10mg -- An erythropoietin mimetic peptide selective for the innate repair receptor, studied for tissue protection, pain reduction, and metabolic support without the erythropoietic effects of full EPO. 10% off with code greats10

Sexual Health and Hormonal:

• PT-141 10mg (https://sigmacompounds.com/products/pt-141/) -- Bremelanotide, a melanocortin receptor agonist with central nervous system mechanism of action for sexual function research. Unlike PDE5 inhibitors that work peripherally, PT-141 works through CNS activation of melanocortin receptors to support arousal research. Studied for both male and female applications. 10% off with code greats10
• Oxytocin 5mg (https://sigmacompounds.com/products/oxytocin/) -- The endogenous "bonding hormone," studied for its roles in social behavior, stress response, bonding, and maternal behavior. Also studied for appetite regulation, pain modulation, and wound healing. 10% off with code greats10
• Kisspeptin-10 10mg (https://sigmacompounds.com/products/kisspeptin-10/) -- A decapeptide that serves as the primary regulator of GnRH secretion in the hypothalamus. Studied for reproductive endocrinology research and gonadotropin regulation. 10% off with code greats10
• Melanotan 1 10mg (https://sigmacompounds.com/products/melanotan-1/) -- Afamelanotide, a full analogue of alpha-MSH studied for melanogenesis (skin darkening) and photoprotection research. Non-selective melanocortin receptor agonist. 10% off with code greats10
• Melanotan 2 10mg (https://sigmacompounds.com/products/melanotan-2/) -- A cyclic analogue of alpha-MSH with shorter structure and broader melanocortin receptor binding. Studied for both tanning and sexual function applications through combined MC1R and MC4R receptor activity. 10% off with code greats10

Antioxidants:

• Glutathione 600mg (https://sigmacompounds.com/products/glutathione/) -- The body's primary endogenous antioxidant and detoxification compound. Studied for oxidative stress reduction, liver protection, immune support, and skin health. 10% off with code greats10
• Glutathione 1500mg (https://sigmacompounds.com/products/glutathione-1500mg/) -- High-dose glutathione for intensive antioxidant research protocols. 10% off with code greats10

Peptide Blends (Synergistic Research Stacks):

• BPC-157/TB-500 10/10mg Blend (https://sigmacompounds.com/products/bpc-157-tb-500-blend/) -- The most popular research peptide combination. BPC-157 works through local angiogenesis and growth factor upregulation; TB-500 works through systemic actin regulation and cell migration. Their complementary mechanisms make this the most widely researched healing peptide combination. 10% off with code greats10
• TB-500 + BPC-157 5/5mg (https://sigmacompounds.com/products/tb-500-bpc-157-5-5-mg/) -- Balanced 5/5mg format of the core BPC-157/TB-500 combination for researchers who prefer equal dosing ratios at lower concentrations. 10% off with code greats10
• CJC-1295/Ipamorelin 5/5mg (https://sigmacompounds.com/products/cjc-1295-ipamorelin/) -- The most studied growth hormone secretagogue combination. CJC-1295 provides sustained GHRH signal; Ipamorelin provides GHRP stimulation with a clean side effect profile. The synergistic combination produces substantially greater GH pulse amplitude than either compound alone. 10% off with code greats10
• Tesamorelin + Ipamorelin 6/2mg (https://sigmacompounds.com/products/tesamorelin-ipamorelin/) -- A dual GH secretagogue stack combining Tesamorelin's GHRH activity with Ipamorelin's GHRP activity for synergistic GH release in a ratio that reflects current research protocols. 10% off with code greats10
• BPC-157/TB-500/GHK-Cu 10/10/50mg GLOW Blend (https://sigmacompounds.com/products/bpc-157-tb-500-ghk-cu/) -- Sigma's triple compound GLOW stack, combining the core repair properties of BPC-157 and TB-500 with the anti-aging, collagen-stimulating, and tissue-regenerating properties of GHK-Cu copper peptide. A comprehensive recovery and regeneration research stack. 10% off with code greats10
• BPC-157/TB-500/KPV/GHK-Cu 10/10/10/50mg KLOW Blend (https://sigmacompounds.com/products/bpc-157-tb-500-kpv-ghk-cu/) -- Sigma's flagship four-compound KLOW stack. Adds KPV (anti-inflammatory tripeptide) to the GLOW blend for comprehensive anti-inflammatory coverage alongside the repair, regeneration, and anti-aging compounds. The most complete single-vial research stack in the Sigma lineup. 10% off with code greats10

Nasal Sprays:

Sigma Compounds offers select peptides in nasal spray format for intranasal delivery -- a well-established alternative delivery route for peptides that are active on the central nervous system. Intranasal delivery provides direct access to the CNS via the olfactory pathway, bypassing the blood-brain barrier for certain compounds.

• BPC-157 Nasal Spray 10mg -- Intranasal BPC-157 for central and peripheral research applications. The nasal spray format delivers BPC-157 to the CNS via the olfactory pathway. 10% off with code greats10
• Selank Nasal Spray 10mg -- Intranasal Selank for cognitive and anxiolytic research. The nootropic and anxiolytic properties of Selank make it particularly well-suited to the nasal spray format for direct CNS access. 10% off with code greats10
• Semax Nasal Spray 10mg -- Intranasal Semax, the delivery format for which Semax was originally developed in Russia. Semax's primary mechanism through BDNF upregulation is particularly relevant to CNS-targeted research via nasal delivery. 10% off with code greats10
• PT-141/Oxytocin Nasal Spray -- Dual-action nasal spray combining PT-141's melanocortin-based sexual function research activity with oxytocin's bonding and arousal-adjacent research applications. 10% off with code greats10

Who Is Sigma Compounds For?

Researchers and scientists working in peptide biology, tissue repair, longevity, metabolic health, or neuroendocrinology who need reliably purity-tested research compounds from a transparent, documented source.

Serious biohackers and self-quantifiers who follow the research literature on therapeutic peptides and want access to the same compounds studied in published research, sourced from a company with established credibility and third-party testing documentation.

Healthcare practitioners who incorporate peptide research into their clinical inquiry and need compounds that meet documentation and purity standards consistent with serious professional use.

Customers of the peptide research space who have been disappointed by anonymous vendors with no accountability and want a company where the founder is publicly known, the testing is documented, and the customer service is genuinely responsive.

Pricing at a Glance

Use code greats10 at checkout for 10% off all orders. Free shipping on all orders over $100.

Why We Recommend Sigma Compounds

In a research peptide market dominated by anonymous vendors of unknown accountability, Sigma Compounds' combination of founder visibility, ISO-certified sourcing, third-party testing, boutique packaging, and genuinely personal customer service creates a trust profile that is exceptionally rare. The GLOW and KLOW blend formulations represent sophisticated compound design -- not just single peptides, but carefully calibrated multi-compound stacks targeting specific research outcomes (comprehensive tissue repair, combined anti-aging and repair, anti-inflammatory plus healing). The nasal spray lineup adds a delivery format that is scientifically appropriate for CNS-active peptides like Selank and Semax.

Find the latest Sigma Compounds coupon codes on this page -- including verified code greats10 for 10% off all orders.